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Medicina (B.Aires) ; 68(5): 373-379, sep.-oct. 2008. mapas, tab
Article in English | LILACS | ID: lil-633571

ABSTRACT

In Río Negro Province, Argentina, human cases of hantavirus pulmonary syndrome (HPS) appeared in the region of subantartic forests. The Andes virus (ANDV) has been identified in the region both in Oligoryzomys longicaudatus rodents and in humans, with the main transmission being from rodents to humans but also showing the possibility of human to human transmission. Between 1996 and 2004, in 40 campaigns, 29.960 night-traps for capturing live rodents were set up. Blood samples were obtained from the rodents and processed using enzyme immunoassay with recombinant antigens made from ANDV. A total of 1767 rodents were captured, with a capture success of 5.9% and an antibody prevalence of 2.1%. Important differences were observed among the species captured from Andes and Steppe regions. Seropositive Oligoryzomys longicaudatus, Abrotrix olivaceus, Abrotrix xanhtothinus and Loxodontomus microtus were captured. During the 1993-2004 period, 40 HPS cases were registered.


En la Provincia de Río Negro, Argentina, se presentaron casos humanos de síndrome pulmonar por hantavirus (SPH) en la región de los bosques subantárticos. El virus Andes (AND) fue identificado en la región, tanto en el roedor Oligoryzomys longicaudatus como en seres humanos, demostrándose la transmisión principalmente del roedor al hombre y la posibilidad de la transmisión de persona a persona. Para ello, se procedió a la colocación de 29.960 trampas para captura viva de roedores, tipo Sherman, en 40 operativos efectuados desde 1996 hasta 2004. Se obtuvieron muestras de sangre de los roedores, las que fueron procesadas mediante enzimoinmunoensayo con antígenos recombinantes elaborados a partir de virus AND. Fueron capturados 1767 roedores, con un éxito de trampeo del 5.9% y una prevalencia de anticuerpos contra hantavirus del 2.1%. Se observaron importantes diferencias en las especies capturadas en cada una de las regiones. Se capturaron O. longicaudatus, Abrothrix olivaceus y Abrothrix xanhtothinus y Loxodontomys microtus seropositivos. Se registraron 40 casos humanos en el período 1993-2004.


Subject(s)
Animals , Female , Humans , Male , Antibodies, Viral/blood , Disease Outbreaks , Hantavirus Pulmonary Syndrome/epidemiology , Hantavirus Pulmonary Syndrome/veterinary , Orthohantavirus/immunology , Rodent Diseases/epidemiology , Argentina/epidemiology , Disease Reservoirs , Hantavirus Pulmonary Syndrome/mortality , Rodent Diseases/blood , Rodent Diseases/virology , Rodentia/virology
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